If I have Factor V Leiden and no one else in my family does what does that mean?
submitted by Liza in Santa Barbara, CA
It means either there was a faulty test or someone is not being honest - either about having the FVL mutation or about your parents...You have to have inherited a mutated gene from your mom or your dad (if you're hetero. If you have 2 genes, homozygous, then BOTH your mother and father HAVE to have at least one mutated gene to have passed on to you). As far as I know, FVL does not "skip" generations. So unless you've always suspected you're adopted, your father is not your "blood" father, or the hospital mistakenly switched you at birth, it had to have been an faulty test - either your positive result is wrong or their negative one is.
It is entirely possible for you to be the only sibling to inherit the disorder, but one of your parents has got to have the gene.
submitted by ANN in MIDWEST
@ June 12, 2009 - 10:49 AM
It is impossible for your parents to both not have the gene. One of them must for it to be passed on to you. Have they even been tested? It is not something that you can get through a transfusion, it is something that you are born with and has been passed down to you from either one parent if you are heterozygeous or both parents if you are homozygeous.
submitted by Kirsty in South Australia
@ July 09, 2009 - 02:18 AM
If your parents have been checked at least twice for FVL then I would suggest you get tested again.
submitted by Jessica in Phoenix, az
@ August 28, 2009 - 05:04 PM
Not true...although unlikely it is possible for you to have developed the mutation without either parent having it. This is my case, we have gone through multiple Factor V testing all of us, and paternity testing. So it is possible for a child to have it without either parent having it. In my case I have the heterozygeous verison.
submitted by melissa in charlotte,nc
@ September 29, 2009 - 05:57 PM
It is entirely possible for you to be the only sibling to inherit the disorder, but one of your parents has got to have the gene.